4-(Methoxymethyl)phenylacetic acid

4-(Methoxymethyl)phenylacetic acid - Names and Identifiers

Name	4-(Methoxymethyl)phenylacetic acid
Synonyms	2-(4-(Methoxymethyl) (4-METHOXYMETHYLPHENYL)ACETIC ACID 4-(Methoxymethyl)phenylacetic acid [4-(Methoxymethyl)phenyl]acetic acid 2-(4-(Methoxymethyl)Phenyl)Acetic Acid 2-(4-(Methoxymethyl)phenyl)acetic acid benzeneacetic acid, 4-(methoxymethyl)-
CAS	343880-24-0
InChI	InChI=1/C10H12O3/c1-13-7-9-4-2-8(3-5-9)6-10(11)12/h2-5H,6-7H2,1H3,(H,11,12)

4-(Methoxymethyl)phenylacetic acid - Physico-chemical Properties

Molecular Formula	C10H12O3
Molar Mass	180.2
Density	1.154±0.06 g/cm3(Predicted)
Boling Point	300.1±22.0 °C(Predicted)
Flash Point	117°C
Vapor Presure	0.000511mmHg at 25°C
pKa	4.29±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.536
MDL	MFCD08060493

4-(Methoxymethyl)phenylacetic acid - Introduction

4-(Methoxymethyl)phenylacetic acid, also known as 4-(methoxymethyl) phenylacetic acid or 4-(Methoxymethyl)phenylacetic acid, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White crystal or crystalline powder at room temperature
-Molecular formula: C10H12O3
-Molecular weight: 180.20g/mol
-Melting point: about 105-110°C
-Boiling point: about 345°C
-Solubility: Soluble in alcohol and ether solvents, slightly soluble in water

Use:
4-(Methoxymethyl)phenylacetic acid can be used:
-Drug synthesis: as an intermediate in the synthesis of antibiotics, anti-inflammatory drugs and other drugs
-Cosmetics: Used as a flavor and fragrance ingredient
-Functional materials: for the synthesis of dyes, solvents and surfactants

Preparation Method:
The preparation method of 4-(Methoxymethyl)phenylacetic acid can be realized by the rearrangement reaction of p-methoxymethylphenylacetic acid. The specific method includes transesterification of methoxymethylphenylacetic acid to give methoxymethylphenylacetic acid, which is then converted to 4-(Methoxymethyl)phenylacetic acid by a rearrangement reaction.

Safety Information:
Under the correct operating conditions, this compound is generally considered to be relatively safe. However, as any chemical, safe handling measures should be followed when using:
-Avoid contact with skin, eyes and mucous membranes
-Use appropriate personal protective equipment, including gloves and protective glasses
-Avoid inhaling its dust or vapor, and the working environment should be well ventilated
-Store away from ignition and oxidizing agents

Please note that the above information is for reference only and is not exhaustive. When using or handling this compound, refer to the relevant chemical literature and safety data sheets, and follow appropriate laboratory practices.

Last Update：2024-04-09 15:17:56